PureLean™ Nutrients

Suggested Use: 4-6 capsules per day, in divided doses, with meals. Not to be taken by pregnant or lactating women.

PureLean™ Nutrients - PureLean™ Nutrients is designed to provide metabolic and weight management support as part of a healthy lifestyle with a reduced calorie diet and regular exercise. It is a complete hypo-allergenic, highly bioavailable multi-vitamin, multi-mineral and trace element supplement. The formula combines superior mineral cofactors, activated vitamins, antioxidants, amino acids, cinnamon, green tea and pterostilbene to support healthy glucose metabolism, lipid utilization and body composition.

Support for healthy glucose metabolism, lipid utilization, body composition and weight management as part of a healthy lifestyle with a reduced calorie diet and regular exercise.* Vitamin/Mineral Distinctions: • High potency, hypo-allergenic, vegetarian formula • Activated vitamins and superior mineral chelates for optimal absorption • Antioxidant support from naturally derived vitamin C, vitamin E, beta carotene, lycopene, lutein, zeaxanthin and alpha lipoic acid* • 800 mcg Metafolin® (6S)-5-methyltetrahydrofolic acid (L-5-MTHF), the naturally occurring, universally metabolized form of folate* • 400 mcg of chromium, from chromium polynicotinate and patented, enhanced bioactivity Chromium 454®, to support Akt metabolic kinase activity and GLUT4 glucose transporter function* • 500 mg of vitamin C, from ascorbic acid and rapid uptake PureWay-C®, for healthy inflammation balance, lipid antioxidant protection, and C-reactive protein metabolism*

Special Features:

• Macular Synergy Complex Enhances the integrity of the macula and retina with lutein and zeaxanthin. Numerous double blind, placebocontrolled trials indicate that lutein and zeaxanthin support the health of the retina and optical lens. Additionally, recent research has revealed that the combination may target different areas in the retina to enhance total retinal health, photoreceptor health, and color vision. Synergistic cofactors include vitamin C, vitamin E, zinc and carotenoids.* • Metabolic GlycoPlex Supports healthy glucose uptake with alpha lipoic acid and cinnamon. Clinical trials report that supplementation with cinnamon promotes healthy glucose balance and is well tolerated. In another study, alpha lipoic acid decreased serum lactate and pyruvate and promoted healthy glucose metabolism in lean and overweight individuals. Furthermore, alpha lipoic acid and l-carnosine help maintain healthy advanced glycation end product metabolism and provide antioxidant protection.* • Metabolic LipidPlex Promotes hepatic fat metabolism with green tea and taurine. Green tea extract has been shown in recent studies to enhance thermogenesis and fat oxidation. Taurine promotes healthy glucose, lipid and triglyceride metabolism. Taurine promotes the formation of taurocholate, a substance that increases cholesterol secretion in the bile and also supports fat metabolism in the liver. Studies reveal that pterostilbene, an antioxidant found in blueberries and the Pterocarpus marsupium tree, may promote healthy PPAR activity to encourage healthy lipid and triglyceride metabolism.*

What Is The Source?

The nutrients found in PureLean Nutrients are derived from the following:

Mixed carotenoids: Blakeslea trispora Lycopene: natural tomato concentrate Lutein††: marigold flower extract Zeaxanthin†: synthetic Vitamin C: corn dextrose fermentation PureWay-C®: corn dextrose fermentation and citrus bioflavonoids Vitamin D3: cholesterol from wool fat (lanolin) Vitamin E: soybean oil Vitamin K1: synthetic Vitamin B1 (thiamine HCl): synthetic Vitamin B2 (riboflavin): corn dextrose fermentation Niacinamide and Niacin: synthetic Vitamin B5 (calcium pantothenate): synthetic Vitamin B6 (pyridoxal HCl): synthetic Vitamin B12 (methylcobalamin): corn dextrose fermentation Metafolin® (6S)-5-methyltetrahydrofolic acid (L-5-MTHF): synthetic Biotin: synthetic Alpha lipoic acid: synthetic l-Carnosine (beta-alanyl-L-histidine) is synthetic Taurine (free-form) is synthetic. Chromium 454®†††† is derived from a proprietary Brewer's yeast extract Minerals: naturally derived from the lime of rock Sources of the mineral chelates include: Citrate: corn dextrose fermentation Glycinate: synthetic Cinnamon extract††††† (10-15:1) is derived from Cinnamomum cassia dried bark. Green tea extract is derived from the leaf and standardized to provide 23% epigallocatechin gallate (EGCG). Pterocarpus marsupium extract is derived from the tree and standardized to contain 5% pterostilbene. †††††CinSulin® is a registered trademark of Tang-An Medical, Ltd. Manufactured under U.S. Patent 6,200,569. ††††Chromium 454® is a registered trademark of VDF FutureCeuticals, Inc, used under license. †††Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany. †† is a registered trademark of Kemin Industries, Inc. †Zeaxanthin is sourced from OPTISHARP™ brand. OPTISHARP™ is a trademark of DSM Nutritional Products, Inc.

Recommendations

Pure Encapsulations recommends per 4-6 capsules per day, in divided doses, with meals.

Are There Any Potential Side Effects Or Precautions?

If pregnant or lactating, consult your physician before taking this product. Green tea has been associated with dizziness, agitation, headache, and gastrointestinal upset, including nausea, bloating, dyspepsia or diarrhea. Rarely, alpha lipoic acid has been associated with skin rash. Consult your physician for more information.Take with food. If you have liver problems, consult your health care practitioner before use. Vitamin K may be contraindicated with Coumadin (Warfarin). If you are pregnant or lactating, have any health condition or are taking any medication, particularly blood thinning medication, consult your health professional before use.

Are There Any Potential Drug Interactions?

Individuals on antidiabetes medications may require blood glucose monitoring. Green tea may be contra-indicated with blood thinning medications. Consult your physician for more information.